Predictability of EEG interictal spikes

Predictability of EEG interictal spikes.

To determine whether EEG spikes are predictable, time series of EEG spike intervals were generated from subdural and depth electrode recordings from four patients. The intervals between EEG spikes were hand edited to ensure high accuracy and eliminate false positive and negative spikes. Spike rates (per minute) were generated from longer time series, but for these data hand editing was usually ...

Source Analysis of Interictal Spikes in EEG and MEG

Simultaneous EEG/MEG and ECoG source characterization of interictal spikes

For some TLE patients that do not respond the pharmacological treatment, epilepsy surgery is an option. In those cases, the determination of the location of the sources and the sequence in which they become active is of prime importance. In this paper, we investigate the interpretability and validity of dipole source localization based on EEG, MEG and simultaneous EEG+MEG for TLE interictal spi...

High-resolution EEG: cortical potential imaging of interictal spikes.

BACKGROUND It is of clinical importance to localize pathologic brain tissue in epilepsy. Noninvasive localization of cortical areas associated with interictal epileptiform spikes may provide important information to facilitate presurgical planning for intractable epilepsy patients. METHODS A cortical potential imaging (CPI) technique was used to deconvolve the smeared scalp potentials into th...

Noninvasive source localization of interictal EEG spikes: effects of signal-to-noise ratio and averaging.

Source localization using single current dipoles estimates equivalent centers of the spiking gray matter. The extent of the active cortex, however, is difficult to assess from scalp EEG because of the unknown individual volume conduction. The spatial scatter of dipole localizations of single spikes has been proposed as a measure of extent. Single spike localization, however, is strongly depende...